Browsing School of Natural Sciences and Mathematics by Title
Now showing items 1-20 of 1001
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(111) Surface States of SnTe
(2014-12--0)The characterization and applications of topological insulators depend critically on their protected surface states, which, however, can be obscured by the presence of trivial dangling bond states. Our first-principle ... -
2d Frequency-Domain Elastic Full-Waveform Inversion Using Time-Domain Modeling and a Multistep-Length Gradient Approach
(Soc Exploration Geophysicists, 2014-02-17)To decouple the parameters in elastic full-waveform inversion (FWI), we evaluated a new multistep-length gradient approach to assign individual weights separately for each parameter gradient and search for an optimal step ... -
3CPET: Finding Co-Factor Complexes from ChIA-Pet Data Using a Hierarchical Dirichlet Process
(BioMed Central Ltd, 2015-12-22)Various efforts have been made to elucidate the cooperating proteins involved in maintaining chromatin interactions; however, many are still unknown. Here, we present 3CPET, a tool based on a non-parametric Bayesian approach, ... -
3D, 9C Seismic Modeling and Inversion of Weyburn Field Data
(2012-06-18)Inversion of 3D, 9C wide azimuth vertical seismic profiling (VSP) data from the Weyburn Field for 21 independent elastic tensor elements was performed based on the Christoffel equation, using slowness and polarization ... -
The 4-D Microgravity Method for Waterflood Surveillance: A Model Study for the Prudhoe Bay Reservoir, Alaska
(Society of Exploration Geophysicists, 1999-01)Forward and inverse gravity modeling is carried out on a suite of reservoir simulations of a proposed water injection on the Prudhoe Bay reservoir, Alaska. A novel surveillance technique is developed in which surface gravity ... -
A Bayesian Latent Variable Approach to Aggregation of Partial and Top-Ranked Lists in Genomic Studies
In genomic research, it is becoming increasingly popular to perform meta-analysis, the practice of combining results from multiple studies that target a common essential biological problem. Rank aggregation, a robust ... -
A Holistic View of Cancer Bioenergetics: Mitochondrial Function and Respiration Play Fundamental Roles in the Development and Progression of Diverse Tumors
Since Otto Warburg made the first observation that tumor cells exhibit altered metabolism and bioenergetics in the 1920s, many scientists have tried to further the understanding of tumor bioenergetics. Particularly, in the ... -
A Multiscale Direct Solver for the Approximation of Flows in High Contrast Porous Media
We consider a non-overlapping domain decomposition approach to approximate the solution of elliptic boundary value problems with high contrast in their coefficients. We propose a method such that initially local solutions ... -
A Multiscale Model to Study the Enhancement in the Compressive Strength of Multi-Walled CNT Sheet Overwrapped Carbon Fiber Composites
The high tensile strength of polymer matrix composites is derived primarily from the high strength of the carbon fibers embedded in the polymer matrix. However, their compressive strength is generally much lower due to the ... -
A Novel Inhibitor of Pyruvate Dehydrogenase Kinase Stimulates Myocardial Carbohydrate Oxidation in Diet-Induced Obesity
The pyruvate dehydrogenase complex (PDC) is a key control point of energy metabolism and is subject to regulation by multiple mechanisms, including posttranslational phosphorylation by pyruvate dehydrogenase kinase (PDK). ... -
A Phenotypic Cell-Binding Screen Identifies a Novel Compound Targeting Triple-Negative Breast Cancer
We describe a "phenotypic cell-binding screen" by which therapeutic candidate targeting cancer cells of a particular phenotype can be isolated without knowledge of drug targets. Chemical library beads are incubated with ... -
A Type I Restriction-Modification System Associated with Enterococcus Faecium Subspecies Separation
(Amer Soc Microbiology, 2019-01-09)The gastrointestinal colonizer Enterococcus faecium is a leading cause of hospital-acquired infections. Multidrug-resistant (MDR) E. faecium isolates are particularly concerning for infection treatment. Previous comparative ... -
Absence of Thermalization in Finite Isolated Interacting Floquet Systems
(Amer Physical Soc, 2018-10-22)Conventional wisdom suggests that the long-time behavior of isolated interacting periodically driven (Floquet) systems is a featureless maximal-entropy state characterized by an infinite temperature. Efforts to thwart this ... -
Accumulation Capacitance Frequency Dispersion of Ⅲ-Ⅴ Metal-Insulator-Semiconductor Devices due to Disorder Induced Gap States
(American Institute of Physics Inc., 2014-07-07)The origin of the anomalous frequency dispersion in accumulation capacitance of metal-insulator-semiconductor devices on InGaAs and InP substrates is investigated using modeling, electrical characterization, and chemical ... -
Activity-Dependent FUS Dysregulation Disrupts Synaptic Homeostasis
(Natl Acad Sciences, 2014-10-16)The RNA-binding protein fused-in-sarcoma (FUS) has been associated with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), two neurodegenerative disorders that share similar clinical and ... -
Acute and Chronic Toxicity of Metal Oxide Nanoparticles in Chemical Mechanical Planarization Slurries with Daphnia Magna
The semiconductor manufacturing industry uses metal oxide nanoparticles (NPs), including colloidal silica (c-SiO₂), fumed silica (f-SiO₂), ceria (CeO₂), and alumina (Al₂O₃), as abrasives in chemical mechanical planarization ... -
Adeno-associated viral serotypes produce differing titers and differentially transduce neurons within the rat basal and lateral amygdala
Background: In recent years, there has been an increased interest in using recombinant adeno-associated viruses (AAV) to make localized genetic manipulations within the rodent brain. Differing serotypes of AAV possess ... -
Adiabatically Tuning Quantized Supercurrents in an Annular Bose-Einstein Condensate
(2018-08-20)The ability to generate and tune quantized persistent supercurrents is crucial for building superconducting or atomtronic devices with novel functionalities. In ultracold atoms, previous methods for generating quantized ... -
Alterations of Specific Chromatin Conformation Affect ATRA-Induced Leukemia Cell Differentiation
Chromatin conformation plays a key role in regulating gene expression and controlling cell differentiation. However, the whole-genome chromatin conformation changes that occur during leukemia cell differentiation are poorly ... -
Altered Amygdala Connectivity in Individuals with Chronic Traumatic Brain Injury and Comorbid Depressive Symptoms
Depression is one of the most common psychiatric conditions in individuals with chronic traumatic brain injury (TBI). Though depression has detrimental effects in TBI and network dysfunction is a "hallmark" of TBI and ...