• The Influence of Oxytocin and Vasopressin on Men's Judgments of Social Dominance and Trustworthiness: An fMRI Study of Neutral Faces 

  Teed, Adam R.; Han, K.; Rakic, J.; Mark, D. B.; Krawczyk, Daniel C.

  Cues signaling trust and dominance are crucial for social life. Previous studies on the effects of oxytocin (OT) nasal sprays on trustworthiness evaluations have been inconsistent and its influence on dominance is unknown. ...

• Transcriptome Analysis of the Human Tibial Nerve Identifies Sexually Dimorphic Expression of Genes Involved in Pain, Inflammation, and Neuro-Immunity 

  Ray, Pradipta R.; Khan, Jawad; Wangzhou, Andi; Tavares-Ferreira, Diana; Akopian, A. N.; Dussor, Gregory; Price, Theodore J.

  Sex differences in gene expression are important contributors to normal physiology and mechanisms of disease. This is increasingly apparent in understanding and potentially treating chronic pain where molecular mechanisms ...

• Leaky Expression of Channelrhodopsin-2 (ChR2) In Ai32 Mouse Lines 

  Prabhakar, Arthi; Vujovic, D.; Cui, L.; Olson, W.; Luo, W.

  Optogenetics enables the selective activation of genetically-targeted neuronal populations using light-sensitive ion channels. Genetic strategies using Cre-dependent mouse strains, especially the Ai32 line expressing ...

• A Speech Processing Strategy Based on Sinusoidal Speech Model for Cochlear Implant Users 

  Lee, Sungmin; Akbarzadeh, Sara; Singh, Satnam; Tan, Chin-Tuan

  In sinusoidal modeling (SM), speech signal, which is pseudo-periodic in structure, can be approximated by sinusoids and noise without losing significant speech information. A speech processing strategy based on this ...

• A Suite of Automated Tools to Quantify Hand and Wrist Motor Function after Cervical Spinal Cord Injury 

  Grasse, Katelyn M.; Hays, Seth A.; Rahebi, Kimiya C.; Warren, Victoria S.; Garcia, Elizabeth A.; Wigginton, Jane G.; Kilgardi Mchael P.; Rennaker, Robert L.

  Background: Cervical spinal cord injury (cSCI) often causes chronic upper extremity disability. Reliable measurement of arm function is critical for development of therapies to improve recovery after cSCI. In this study, ...

• Michigan Neural Distinctiveness (MiND) Study Protocol: Investigating the Scope, Causes, and Consequences of Age-Related Neural Dedifferentiation 

  Gagnon, H.; Simmonite, M.; Cassady, K.; Chamberlain, J.; Freiburger, E.; Lalwani, P.; Kelley, S.; Foerster, B.; Park, Denise C.; Petrou, M.; Seidler, R. D.; Taylor, S. F.; Weissman, D. H.; Polk, T. A.

  Background: Aging is often associated with behavioral impairments, but some people age more gracefully than others. Why? One factor that may play a role is individual differences in the distinctiveness of neural representations. ...

• The Search for Noise-Induced Cochlear Synaptopathy in Humans: Mission Impossible? 

  Bramhall, N.; Beach, E. F.; Epp, B.; Le Prell, Colleen G.; Lopez-Poveda, E. A.; Plack, C. J.; Schaette, R.; Verhulst, S.; Canlon, B.

  Animal studies demonstrate that noise exposure can permanently damage the synapses between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and there is no clinically relevant permanent ...

• Vagus Nerve Stimulation Rate and Duration Determine Whether Sensory Pairing Produces Neural Plasticity 

  Buell, Elizabeth P.; Borland, Michael S.; Loerwald, Kristopher W.; Chandler, Collin; Hays, Seth A.; Engineer, Crystal T.; Kilgard, Michael P.

  Repeatedly pairing a brief train of vagus nerve stimulation (VNS) with an auditory stimulus drives reorganization of primary auditory cortex (A1), and the magnitude of this VNS-dependent plasticity is dependent on the ...

• Multiparity Affects Conduction Properties of Pelvic Floor Nerves in Rabbits 

  Castelán, F.; López-García, K.; Moreno-Pérez, S.; Zempoalteca, R.; Corona-Quintanilla, D. L.; Romero-Ortega, Mario I.; Jiménez-Estrada, I.; Martínez-Gómez, M.

  Introduction: Women often develop pelvic floor dysfunction due to damage to the pelvic musculature during childbirth; however, the effect on pelvic floor nerves function is less understood. This study used adult rabbits ...

• The Functional Alterations in Top-Down Attention Streams of Parkinson's Disease Measured by EEG 

  Bin Yoo, Hye; de la Concha, Edward Omar; De Ridder, D.; Pickut, B. A.; Vanneste, Sven

  Early and moderate Parkinson's disease patients seem to have attention dysfunctions manifested differentially in separate attention streams: Top-down and bottom-up. With a focus on the neurophysiological underpinnings of ...

• Neural Mechanisms of Behavioral Change in Young Adults with High-Functioning Autism Receiving Virtual Reality Social Cognition Training: A Pilot Study 

  Yang, Y. J. Daniel; Allen, Tandra; Abdullahi, Sebiha M.; Pelphrey, Kevin A.; Volkmar, Fred R.; Chapman, Sandra Bond

  Measuring treatment efficacy in individuals with Autism Spectrum Disorder (ASD) relies primarily on behaviors, with limited evidence as to the neural mechanisms underlying these behavioral gains. This pilot study addresses ...

• The Value of Clinical and Ultrasound Features for the Diagnosis of Infantile Hepatic Hemangioma: Comparison with Contrast-Enhanced CT/MRI 

  Xu, M.; Pan, F. -S; Wang, W.; Zhang, X. -E; Li, X. -J; Hong, Yu; Zhou, L. -Y; Xie, X. -Y; Lyu, M. -D

  Objectives: To investigate the combined use of ultrasound together with clinical features to differentiate infantile hepatic hemangioma (IHH) from other focal liver lesions (FLLs) in children and to compare the efficacy ...

• Which Levels of Cognitive Impairments and Negative Symptoms Are Related to Functional Deficits in Schizophrenia? 

  Strassnig, M.; Bowie, C.; Pinkham, Amy E.; Penn, D.; Twamley, E. W.; Patterson, T. L.; Harvey, P. D.

  Background: Negative symptoms and cognitive impairments predict difficulties in aspects of everyday functioning in schizophrenia, with little research to date attempting to determine if there are threshold levels of ...

• Preschoolers Sometimes Seek Help from Socially Engaged Informants over Competent Ones 

  Rowles, Sydney P.; Mills, Candice M.

  The current studies examine whether children can selectively seek help from more competent others to solve simple problems. Across two experiments, 4- and 5-year-old children watched two adults demonstrate using a toy: one ...

• Spinal Inhibition of P2XR or p38 Signaling Disrupts Hyperalgesic Priming in Male, but not Female, Mice 

  Paige, Candler; Maruthy, Gayathri B.; Mejia, Galo; Dussor, Gregory; Price, Theodore J.

  Recent studies have demonstrated sexual dimorphisms in the mechanisms contributing to the development of chronic pain. Here we tested the hypothesis that microglia might preferentially regulate hyperalgesic priming in male ...

• Optimization of Transcranial Direct Current Stimulation of Dorsolateral Prefrontal Cortex for Tinnitus: A Non-Linear Dose-Response Effect 

  Shekhawat, Giriraj Singh; Vanneste, Sven; Shekhawat, Giriraj Singh

  Neuromodulation is defined as the process of augmenting neuroplasticity via invasive or non-invasive methods. Tinnitus is the perception of sound in the absence of its external source. The objective of this study was to ...

• Transcranial Magnetic Stimulation of the Left Angular Gyrus During Encoding Does not Impair Associative Memory Performance 

  Koen, Joshua D.; Thakral, P. P.; Rugg, Michael D.

  The left angular gyrus (AG) is thought to play a critical role in episodic retrieval and has been implicated in the recollection of specific details of prior episodes. Motivated by recent fMRI studies in which it was ...

• Social Cognitive Impairments in Individuals with Schizophrenia Vary in Severity 

  Hajdúk, M.; Harvey, P. D.; Penn, D. L.; Pinkham, Amy E.

  Social cognitive deficits are a hallmark feature of schizophrenia and have been confirmed by several meta-analyses; however, the uniformity of these impairments across individuals remains unknown. The present study evaluated ...

• Targeted Acid-Sensing Ion Channel Therapies for Migraine 

  Karsan, Nazia; Gonzales, Eric B.; Dussor, Gregory

  Acid-sensing ion channels (ASICs) are a family of ion channels, consisting of four members; ASIC1 to 4. These channels are sensitive to changes in pH and are expressed throughout the central and peripheral nervous ...

• Relations Between Parent Psychological Control and Parent and Adolescent Social Aggression 

  Meter, D. J.; Ehrenreich, S. E.; Underwood, Marion K.

  Parent-child interactions and parenting behavior may be related to social aggression among adolescents, and adolescents’ social aggression may relate to parents’ social aggression. This study investigated (a) whether parent ...

View more