The mission of the School of Behavioral and Brain Sciences is to understand the intersection of mind, brain and behavior; enhance the health, education, and quality of life of children and families; and create and implement technologies and therapies that repair and strengthen human abilities. We accomplish these goals by recruiting and supporting outstanding faculty to conduct innovative research and student training in a climate that fosters collaboration across

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  • Hearing Healthcare in Remote or Resource-Constrained Environments 

    Swanepoel, D.; Clark, Jackie L. (Cambridge Univ Press, 2018-07-19)
    Background Hearing loss is a leading contributor to the global burden of disease, with more than 80 per cent of affected persons residing in low- and middle-income countries, typically where hearing health services are ...
  • Vagus Nerve Stimulation as a Tool for Enhancing Extinction in Exposure-Based Therapies 

    Noble, Lindsey J.; Souza, Rimenez R.; McIntyre, Christa K. (Springer, 2019-01)
    Rationale Emotionally traumatic experiences can lead to maladaptive memories that are enduring and intrusive. The goal of exposure-based therapies is to extinguish conditioned fears through repeated, unreinforced exposures ...
  • The Relationship Between Age, Neural Differentiation, and Memory Performance 

    Koen, Joshua D.; Hauck, Nedra; Rugg, Michael D. (Society for Neuroscience, 2018-11-02)
    Healthy aging is associated with decreased neural selectivity (dedifferentiation) in category-selective cortical regions. This finding has prompted the suggestion that dedifferentiation contributes to age-related cognitive ...
  • The Antidiabetic Drug Metformin Prevents and Reverses Neuropathic Pain and Spinal Cord Microglial Activation in Male but not Female Mice 

    Inyang, Kufreobong E.; Szabo-Pardi, Thomas; Wentworth, Emma; McDougal, Timothy A.; Dussor, Gregory; Burton, Michael D.; Price, Theodore J. (Academic Press Ltd- Elsevier Science Ltd, 2018-11-01)
    Metformin is a widely prescribed drug used in the treatment of type II diabetes. While the drug has many mechanisms of action, most of these converge on AMP activated protein kinase (AMPK), which metformin activates. AMPK ...
  • Some Prospective Alternatives for Treating Pain: The Endocannabinoid System and its Putative Receptors GPR18 and GPR55 

    Guerrero-Alba, Raquel; Barragán-Iglesias, Paulino; Gonzalez-Hernandez, Abimael; Valdez-Morales, Eduardo E.; Granados-Soto, Vinicio; Condes-Lara, Miguel; Rodriguez, Martin G.; Marichal-Cancino, Bruno A. (Frontiers Media SA, 2019-01-08)
    Background: Marijuana extracts (cannabinoids) have been used for several millennia for pain treatment. Regarding the site of action, cannabinoids are highly promiscuous molecules, but only two cannabinoid receptors (CB₁ ...
  • Tinnitus and Neuropathic Pain Share a Common Neural Substrate in the Form of Specific Brain Connectivity and Microstate Profiles 

    Vanneste, Sven; To, Wing Ting; De Ridder, Dirk (Pergamon-Elsevier Science Ltd, 2018-08-22)
    Tinnitus and neuropathic pain share similar pathophysiological, clinical, and treatment characteristics. In this EEG study, a group of tinnitus (n = 100) and neuropathic pain (n = 100) patients are compared to each other ...
  • Top-Down and Bottom-Up Regulated Auditory Phantom Perception 

    Vanneste, Sven; Alsalman, Ola; De Ridder, Dirk (Soc Neuroscience, 2019-01-09)
    Auditory phantom percepts such as tinnitus are associated with auditory deafferentation. The idea is that auditory deafferentation limits the amount of information the brain can acquire to make sense of the world. Because ...
  • Current Conceptualizations of Narcissism 

    Ackerman, Robert A.; Donnellan, M. Brent; Wright, Aidan G. C. (Lippincott Williams & Wilkins, 2019-01)
    Purpose of review: Definitions of narcissism have traditionally differed across psychiatry and subfields of psychology. This review aims to highlight emerging points of consensus and suggest further directions needed to ...
  • Activation of the Integrated Stress Response in Nociceptors Drives Methylglyoxal-Induced Pain 

    Barragan-Iglesias, Paulino; Kuhn, Jasper; Vidal-Cantu, Guadalupe C.; Belen Salinas-Abarca, Ana; Granados-Soto, Vinicio; Dussor, Gregory; Campbell, Zachary T.; Price, Theodore J. (Lippincott Williams & Wilkins, 2019-01)
    Methylglyoxal (MGO) is a reactive glycolytic metabolite associated with painful diabetic neuropathy at plasma concentrations between 500 nM and 5 μM. The mechanisms through which MGO causes neuropathic pain at these ...
  • First Impressions of Adults with Autism Improve with Diagnostic Disclosure and Increased Autism Knowledge of Peers 

    Sasson, Noah J.; Morrison, Kerrianne E. (Sage Publications Ltd, 2017-10-17)
    A practical consideration for many intellectually able adults with autism spectrum disorder (ASD) is whether to disclose their diagnostic status or try to mask their autistic characteristics to avoid judgment and discrimination. ...
  • Vagus Nerve Stimulation Promotes Generalization of Conditioned Fear Extinction and Reduces Anxiety in Rats 

    Noble, Lindsey J.; Meruva, Venkat B.; Hays, Seth A.; Rennaker, Robert L.; Kilgard, Michael P.; McIntyre, Christa K. (Elsevier Science Inc, 2018-09-21)
    Background: Exposure-based therapies are used to treat a variety of trauma- and anxiety-related disorders by generating successful extinction following cue exposure during treatment. The development of adjuvant strategies ...
  • Frontoparietal Cortical Thickness Mediates the Effect of COMT Val¹⁵⁸Met Polymorphism on Age-Associated Executive Function 

    Miranda, Giuseppe G.; Rodrigue, Karen M.; Kennedy, Kristen M. (Elsevier Science Inc, 2018-09-21)
    Proper dopamine (DA) signaling is likely necessary for maintaining optimal cognitive performance as we age, particularly in prefrontal-parietal networks and in fronto-striatal networks. Thus, reduced DA availability is a ...
  • "I Want to Know More!": Children are Sensitive to Explanation Quality when Exploring New Information 

    Mills, Candice M.; Sands, Kaitlin R.; Rowles, Sydney P.; Campbell, Ian L. (Wiley, 2019-01)
    When someone encounters an explanation perceived as weak, this may lead to a feeling of deprivation or tension that can be resolved by engaging in additional learning. This study examined to what extent children respond ...
  • Tinnitus Distress: A Paradoxical Attention to the Sound? 

    Kandeepan, S.; Maudoux, A.; Ribeiro de Paula, D.; Zheng, J. Y.; Cabay, J. E.; Gómez, F.; Chronik, B. A.; Ridder, D.; Vanneste, Sven; Soddu, A. (Springer-Verlag GmbH and Co., 2019-05-31)
    Tinnitus, the perception of sound in the absence of external stimuli, is often a disturbing symptom for which the underlying functional neuroanatomy still remains poorly understood. Most studies have focused solely on ...
  • Meta-Analysis of Functional Subdivisions within Human Posteromedial Cortex 

    Huang, Yuefeng; Hullfish, Jeffrey; De Ridder, Dirk; Vanneste, Sven (Springer Heidelberg, 2018-10-26)
    The posteromedial cortex (PMC) comprising posterior cingulate cortex (PCC), retrosplenial cortex (RSC), and the precuneus (PrC) is perhaps best known for its involvement in the default mode network. There is no consensus ...
  • Protease Activated Receptor 2 (PAR2) Activation Causes Migraine-Like Pain Behaviors in Mice 

    Hassler, Shayne N.; Ahmad, Fatima B.; Burgos-Vega, Carolina C.; Boitano, Scott; Vagner, Josef; Price, Theodore J.; Dussor, Gregory (Sage Publications Ltd, 2018-05-31)
    Background Pain is the most debilitating symptom of migraine. The cause of migraine pain likely requires activation of meningeal nociceptors. Mast cell degranulation, with subsequent meningeal nociceptor activation, has ...
  • Implicit and Explicit Bodily Emotions and Social Functioning in Schizophrenia 

    Hajduk, M.; Klein, Hans S.; Springfield, Cassi R.; Bass, E.; Pinkham, Amy E. (Elsevier Science BV, 2019-02-12)
    No abstract available. From the text: "The aim of the present study is to analyze whether explicit and implicit recognition of bodily emotions predicts interpersonal functioning in patients with schizophrenia. The secondary ...
  • Non-Invasive Dural Stimulation in Mice: A Novel Preclinical Model of Migraine 

    Burgos-Vega, Carolina Christina; Quigley, Lilyana D.; dos Santos, Gabriela Trevisan; Yan, Flora; Asiedu, Marina; Jacobs, Blaine; Motina, Marina; Safdar, Nida; Yousuf, Hayyan; Avona, Amanda; Price, Theodore J.; Dussor, Greg (Sage Publications Ltd, 2018-05-31)
    Background Migraine is characterized by a collection of neurological symptoms in the absence of injury or damage. However, several common preclinical migraine models require significant damage to the skull to stimulate the ...
  • Social Trait Information in Deep Convolutional Neural Networks Trained for Face Identification 

    Parde, Connor J.; Hu, Ying; Castillo, C.; Sankaranarayanan, S.; O'Toole, Alice J. (Wiley-Blackwell Publishing, 2019-05-27)
    Faces provide information about a person's identity, as well as their sex, age, and ethnicity. People also infer social and personality traits from the face — judgments that can have important societal and personal ...
  • Progress Update from the Hippocampal Subfields Group 

    Olsen, R. K.; Carr, V. A.; Daugherty, A. M.; La Joie, R.; Amaral, R. S. C.; Amunts, K.; Augustinack, J. C.; Kennedy, Kristen M.; Rodrigue, Karen M.; Hippocampal Subfields Group (Elsevier Inc., 2019-06-13)
    Introduction: Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies. We aim to ...

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