Lan Ma is an assistant professor in Bioengineering. Her research interests include
- Elucidate mechanisms underlying circadian rhythms in a model system using an integrated mathematical and experimental approach
- Mathematical modeling of protein-protein interaction in relationship to programmed cell death
- Robustness analysis of circadian rhythm and other oscillatory biological systems
- Applying control theory and dynamical systems theory to the studies of biological systems
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Mir-192-Mediated Positive Feedback Loop Controls the Robustness of Stress-Induced P53 Oscillations in Breast Cancer Cells The p53 tumor suppressor protein plays a critical role in cellular stress and cancer prevention. A number of post-transcriptional regulators, termed microRNAs, are closely connected with the p53-mediated cellular networks. ...
An oscillator consisting of KaiA, KaiB, and KaiC proteins comprises the core of cyanobacterial circadian clock. While one key reaction in this process-KaiC phosphorylation-has been extensively investigated and modeled, ...