Now showing items 1-3 of 3
Reconstructing Cell Cycle Pseudo Time-Series Via Single-Cell Transcriptome Data
(Nature Publishing Group, 2018-08-24)
Single-cell mRNA sequencing, which permits whole transcriptional profiling of individual cells, has been widely applied to study growth and development of tissues and tumors. Resolving cell cycle for such groups of cells ...
Super-Resolution Imaging of a 2.5 Kb Non-Repetitive DNA in situ in the Nuclear Genome Using Molecular Beacon Probes
High-resolution visualization of short non-repetitive DNA in situ in the nuclear genome is essential for studying looping interactions and chromatin organization in single cells. Recent advances in fluorescence in situ ...
Emergent Lévy Behavior In Single-cell Stochastic Gene Expression
(American Physical Society, 2018-08-20)
Single-cell gene expression is inherently stochastic; its emergent behavior can be defined in terms of the chemical master equation describing the evolution of the mRNA and protein copy numbers as the latter tends to ...