Now showing items 1-4 of 4
Gene Module Based Regulator Inference Identifying miR-139 as a Tumor Suppressor in Colorectal Cancer
(Royal Society of Chemistry, 2014-09-30)
Colorectal cancer is one of the most commonly diagnosed cancer types worldwide. Identification of the key regulators of the altered biological networks is crucial for understanding the complex molecular mechanisms of ...
Emergent Lévy Behavior In Single-cell Stochastic Gene Expression
(American Physical Society, 2018-08-20)
Single-cell gene expression is inherently stochastic; its emergent behavior can be defined in terms of the chemical master equation describing the evolution of the mRNA and protein copy numbers as the latter tends to ...
Distinct and Predictive Histone Lysine Acetylation Patterns at Promoters, Enhancers, and Gene Bodies
(Genetics Society America, 2014-11-01)
In eukaryotic cells, histone lysines are frequently acetylated. However, unlike modifications such as methylations, histone acetylation modifications are often considered redundant. As such, the functional roles of distinct ...
Integrated Omics Study Delineates the Dynamics of Lipid Droplets in Rhodococcus Opacus PD630
(Oxford University Press, 2013-10-22)
Rhodococcus opacus strain PD630 (R. opacus PD630), is an oleaginous bacterium, and also is one of few prokaryotic organisms that contain lipid droplets (LDs). LD is an important organelle for lipid storage but also ...