Now showing items 19-21 of 21

    • Quantitative liver-specific protein fingerprint in blood: A signature for hepatotoxicity 

      Hu, Z.; Lausted, C.; Yoo, Hyuntae; Yan, X.; Brightman, A.; Chen, J.; Wang, W.; Bu, X.; Hood, L. (2014-01-14)
      We discuss here a new approach to detecting hepatotoxicity by employing concentration changes of liver-specific blood proteins during disease progression. These proteins are capable of assessing the behaviors of their ...
    • Synthetic Mammalian Transgene Negative Autoregulation 

      Shimoga, Vinay; White, Jacob T.; Li, Yi; Sontag, Eduardo; Bleris, Leonidas (2013-06-04)
      Biological networks contain overrepresented small-scale topologies, typically called motifs. A frequently appearing motif is the transcriptional negative-feedback loop, where a gene product represses its own transcription. ...
    • Transcripts for Combined Synthetic MicroRNA and Gene Delivery 

      Kashyap, Neha; Pham, Bich; Xie, Zhen; Bleris, Leonidas (2013-06-26)
      MicroRNAs (miRNAs) are a class of short noncoding RNAs which are endogenously expressed in many organisms and regulate gene expression by binding to messenger RNA (mRNA). MicroRNAs are either produced from their independent ...