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    • CRISPR-Based Self-Cleaving Mechanism for Controllable Gene Delivery in Human Cells 

      Moore, Richard; Spinhirne, Alec; Lai, Michael J.; Preisser, Samantha; Li, Yi; Kang, Taek; Bleris, Leonidas (Oxford University Press, 2014-12-18)
      Controllable gene delivery via vector-based systems remains a formidable challenge in mammalian synthetic biology and a desirable asset in gene therapy applications. Here, we introduce a methodology to control the copies ...