Browsing Kilgard, Michael P. by Title
Now showing items 7-13 of 13
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Norepinephrine and Serotonin are Required for Vagus Nerve Stimulation Directed Cortical Plasticity
(Academic Press Inc., 2019-06-07)Vagus nerve stimulation (VNS) paired with forelimb training drives robust, specific reorganization of movement representations in the motor cortex. This effect is hypothesized to be mediated by VNS-dependent engagement of ... -
Pairing Sound with Vagus Nerve Stimulation Modulates Cortical Synchrony and Phase Coherence in Tinnitus: An Exploratory Retrospective Study
Recent research has shown that vagus nerve stimulation (VNS) paired with tones or with rehabilitative training can help patients to achieve reductions in tinnitus perception or to expedite motor rehabilitation after suffering ... -
Similarity of Cortical Activity Patterns Predicts Generalization Behavior
Humans and animals readily generalize previously learned knowledge to new situations. Determining similarity is critical for assigning category membership to a novel stimulus. We tested the hypothesis that category membership ... -
Speech Sound Processing Deficits and Training-Induced Neural Plasticity in Rats with Dyslexia Gene Knockdown
In utero RNAi of the dyslexia-associated gene Kiaa0319 in rats (KIA-) degrades cortical responses to speech sounds and increases trial-by-trial variability in onset latency. We tested the hypothesis that KIA- rats would ... -
Vagus Nerve Stimulation Promotes Generalization of Conditioned Fear Extinction and Reduces Anxiety in Rats
(Elsevier Science Inc, 2018-09-21)Background: Exposure-based therapies are used to treat a variety of trauma- and anxiety-related disorders by generating successful extinction following cue exposure during treatment. The development of adjuvant strategies ... -
Vagus Nerve Stimulation Rate and Duration Determine Whether Sensory Pairing Produces Neural Plasticity
Repeatedly pairing a brief train of vagus nerve stimulation (VNS) with an auditory stimulus drives reorganization of primary auditory cortex (A1), and the magnitude of this VNS-dependent plasticity is dependent on the ... -
Vagus Nerve Stimulation Reverses the Extinction Impairments in a Model of PTSD with Prolonged and Repeated Trauma
(Taylor and Francis Ltd, 2019-04-23)We have shown that vagus nerve stimulation (VNS) enhances extinction of conditioned fear and reduces anxiety in rat models of PTSD using moderate stress. However, it is still unclear if VNS can be effective in enhancing ...