Sherry, A. Dean

 

Dean Sherry is a Professor of Chemistry and holds the Cecil H. and Ida Green Distinguished Chair in Systems Biology. He holds a joint appointment as Professor of Radiology at UT Southwestern Medical Center where he also serves as director of the Advanced Imaging Research Center. His research interests involve "the design of novel MR imaging agents that are responsive to physiology and metabolism." Learn more about Professor Sherry on his Faculty profile, Endowed Professorships and Chairs, UT Southwestern Faculty Profile, Sherry Lab and Research Explorer pages.

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Recent Submissions

  • In Vivo Assessment of Increased Oxidation of Branched-Chain Amino Acids in Glioblastoma 

    Suh, Eul Hyun; Hackett, Edward P.; Wynn, R. Max; Chuang, David T.; Zhang, Bo; Luo, Weibo; Sherry, A. Dean; Park, Jae Mo (Nature Publishing Group, 2019-01-23)
    Altered branched-chain amino acids (BCAAs) metabolism is a distinctive feature of various cancers and plays an important role in sustaining tumor proliferation and aggressiveness. Despite the therapeutic and diagnostic ...

  • A Novel Inhibitor of Pyruvate Dehydrogenase Kinase Stimulates Myocardial Carbohydrate Oxidation in Diet-Induced Obesity 

    Wu, C. -Y; Satapati, S.; Gui, W.; Max Wynn, R.; Sharma, G.; Lou, M.; Qi, X.; Burgess, S. C.; Malloy, C.; Khemtong, C.; Sherry, A. Dean; Chuang, D. T.; Merritt, M. E.
    The pyruvate dehydrogenase complex (PDC) is a key control point of energy metabolism and is subject to regulation by multiple mechanisms, including posttranslational phosphorylation by pyruvate dehydrogenase kinase (PDK). ...

  • Influence of Dy³⁺ and Tb³⁺ Doping on ¹³C Dynamic Nuclear Polarization 

    Niedbalski, Peter; Parish, Christopher; Kiswandhi, Andhika; Fidelino, L.; Khemtong, C.; Hayati, Z.; Song, L.; Martins, Andr©; Sherry, A. Dean; Lumata, Lloyd L. (American Institute of Physics Inc, 2017-01-03)
    Dynamic nuclear polarization (DNP) is a technique that uses a microwave-driven transfer of high spin alignment from electrons to nuclear spins. This is most effective at low temperature and high magnetic field, and with ...

  • A Novel Class of Polymeric pH-Responsive MRI CEST Agents 

    Zhang, Shanrong; Zhou, K.; Huang, G.; Takahashi, Masaya; Sherry, A. Dean; Gao, Jinming (2013-05-26)
    In this communication, we report that ionizable, tertiary amine-based block copolymers can be used as pH-responsive contrast agents for magnetic resonance imaging (MRI) through the chemical exchange saturation transfer ...

  • A Europium(Ⅲ)-Based PARACEST Agent for Sensing Singlet Oxygen by MRI 

    Song, Bo; Wu, Yunkou; Yu, Mengxiao; Zhao, Piyu; Zhou, Chen; Kiefer, Garry E.; Sherry, A. Dean (2013-04-04)
    A europium(Ⅲ) DOTA-tetraamide complex was designed as a MRI sensor of singlet oxygen (¹O₂). The water soluble, thermodynamically stable complex reacts rapidly with ¹O₂ to form an endoperoxide derivative that results in an ...