Rennaker, Robert L.
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Robert Rennaker is an Associate Professor, holder of the Cecil H. and Ida Green Chair in Systems Biology Science, and head of the Texas Biomedical Device Center. in 2015 he was awarded the Texas Instruments Distinguished Chair in Bioengineering. Learn more about him on his BBS People, Endowed Professorships and Chairs and Research Explorer pages.
Works in Treasures @ UT Dallas are made available exclusively for educational purposes such as research or instruction. Literary rights, including copyright for published works held by the creator(s) or their heirs, or other third parties may apply. All rights are reserved unless otherwise indicated by the copyright owner(s).
Recent Submissions
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Vagus Nerve Stimulation Promotes Generalization of Conditioned Fear Extinction and Reduces Anxiety in Rats
(Elsevier Science Inc, 2018-09-21)Background: Exposure-based therapies are used to treat a variety of trauma- and anxiety-related disorders by generating successful extinction following cue exposure during treatment. The development of adjuvant strategies ... -
Vagus Nerve Stimulation Reverses the Extinction Impairments in a Model of PTSD with Prolonged and Repeated Trauma
(Taylor and Francis Ltd, 2019-04-23)We have shown that vagus nerve stimulation (VNS) enhances extinction of conditioned fear and reduces anxiety in rat models of PTSD using moderate stress. However, it is still unclear if VNS can be effective in enhancing ... -
Enhancing Plasticity in Central Networks Improves Motor and Sensory Recovery after Nerve Damage
(Springer Nature, 2019-12-19)Nerve damage can cause chronic, debilitating problems including loss of motor control and paresthesia, and generates maladaptive neuroplasticity as central networks attempt to compensate for the loss of peripheral connectivity. ... -
A Suite of Automated Tools to Quantify Hand and Wrist Motor Function after Cervical Spinal Cord Injury
Background: Cervical spinal cord injury (cSCI) often causes chronic upper extremity disability. Reliable measurement of arm function is critical for development of therapies to improve recovery after cSCI. In this study, ... -
Closed-Loop Neuromodulation Restores Network Connectivity and Motor Control After Spinal Cord Injury
Recovery from serious neurological injury requires substantial rewiring of neural circuits. Precisely-timed electrical stimulation could be used to restore corrective feedback mechanisms and promote adaptive plasticity ... -
Pairing Sound with Vagus Nerve Stimulation Modulates Cortical Synchrony and Phase Coherence in Tinnitus: An Exploratory Retrospective Study
Recent research has shown that vagus nerve stimulation (VNS) paired with tones or with rehabilitative training can help patients to achieve reductions in tinnitus perception or to expedite motor rehabilitation after suffering ... -
Retinal Architecture and Melanopsin-Mediated Pupillary Response Characteristics a Putative Pathophysiologic Signature for the Retino-Hypothalamic Tract in Multiple Sclerosis
IMPORTANCE A neurophysiologic signature of the melanopsin-mediated persistent constriction phase of the pupillary light reflex may represent a surrogate biomarker for the integrity of the retinohypothalamic tract, with ... -
Effects of Vagus Nerve Stimulation on Extinction of Conditioned Fear and Post-Traumatic Stress Disorder Symptoms in Rats
Exposure-based therapies help patients with post-traumatic stress disorder (PTSD) to extinguish conditioned fear of trauma reminders. However, controlled laboratory studies indicate that PTSD patients do not extinguish ... -
A Within-Animal Comparison of Skilled Forelimb Assessments in Rats
A variety of skilled reaching tasks have been developed to evaluate forelimb function in rodent models. The single pellet skilled reaching task and pasta matrix task have provided valuable insight into recovery of forelimb ... -
Speech Sound Processing Deficits and Training-Induced Neural Plasticity in Rats with Dyslexia Gene Knockdown
In utero RNAi of the dyslexia-associated gene Kiaa0319 in rats (KIA-) degrades cortical responses to speech sounds and increases trial-by-trial variability in onset latency. We tested the hypothesis that KIA- rats would ... -
Studies in RF Power Communication, SAR, and Temperature Elevation in Wireless Implantable Neural Interfaces
Implantable neural interfaces are designed to provide a high spatial and temporal precision control signal implementing high degree of freedom real-time prosthetic systems. The development of a Radio Frequency (RF) wireless ...