Kim, Tae Hoon
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Tae Hoon Kim serves as an Associate Professor of Biological Sciences. His research focuses on the mechanisms of human genome expression involving transcription insulation, transcription elongation, and long range chromosomal interactions. He is also the founder and head of UTD's Functional Genomics Laboratory.
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Long Genes Linked to Autism Spectrum Disorders Harbor Broad Enhancer-Like Chromatin Domains
Genetic variants associated with autism spectrum disorders (ASDs) are enriched in genes encoding synaptic proteins and chromatin regulators. Although the role of synaptic proteins in ASDs is widely studied, the mechanism ... -
Boundary Associated Long Noncoding RNA Mediates Long-Range Chromosomal Interactions
(Public Library of Science, 2015-08-24)CCCTC binding factor (CTCF) is involved in organizing chromosomes into mega base-sized, topologically associated domains (TADs) along with other factors that define sub-TAD organization. CTCF-Cohesin interactions have been ... -
A Novel Virus-Inducible Enhancer of the Interferon-β Gene with Tightly Linked Promoter and Enhancer Activities
(2014-10-27)Long-range enhancers of transcription are a key component of the genomic regulatory architecture. Recent studies have identified bi-directionally transcribed RNAs emanating from these enhancers known as eRNAs. However, it ...