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Responsive Agents Detecting Biomarkers with Magnetic Resonance Imaging
Paramagnetic chemical exchange saturation transfer (paraCEST) is a novel technique used in magnetic resonance imaging that offers several advantages over the traditional gadolinium T1 agents. In this dissertation, I aimed ...
Optimized Assembly and Utilization of Functional Materials Towards Designing Stable and Reliable Affinity Based Biosensing Platforms
A wide variety of biomarkers are found in human sweat such as electrolytes, metabolites, small molecules and proteins. This renders human sweat to be highly suitable for non-invasive, lancet-free diagnosis of biomarkers. ...
Unraveling Alzheimer's Disease: Relations Between Neuroimaging and Neuropsychological Measures
Alzheimer’s Disease (AD) is a multifaceted disease that includes psychiatric, cognitive, and neurologic components. To better understand the progression of AD it is important to investigate how cognition and neuroimaging ...
Passively Addressable Electrochemical Sensor for Detection of Chloride Ions in Ultra-Low Volumes of Human Sweat
Sweat chloride serves as the gold standard biomarker for diagnosis of Cystic Fibrosis (CF), a lethal progressive, genetic disorder of childhood. Quantification of chloride concentration in human sweat can also be used ...