Kennedy, Kristen M.
Kristen Kennedy is an Assistant Professor in Behavioral and Brain Sciences and the Center for Vital Longevity. She also heads the Kennedy Neuroimaging of Aging and Cognition Lab. She is best known for her research in the area of cognitive neuroscience of aging. Currently, her research interests include
- Normal aging of human brain structure and function,
- Cognitive consequences of aging on health and lifestyle,
- Genetic modifiers of the age-related changes in the brain and cognition
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Frontostriatal White Matter Connectivity: Age Differences and Associations with Cognition and BOLD Modulation (Elsevier Inc., 2020-06-07)Despite the importance of cortico-striatal circuits to cognition, investigation of age effects on the structural circuitry connecting these regions is limited. The current study examined age effects on frontostriatal white ...
Genetic Predisposition for Inflammation Exacerbates Effects of Striatal Iron Content on Cognitive Switching Ability in Healthy Aging (Academic Press Inc Elsevier Science, 2018-10-25)Non-heme iron homeostasis interacts with inflammation bidirectionally, and both contribute to age-related decline in brain structure and function via oxidative stress. Thus, individuals with genetic predisposition for ...
Frontoparietal Cortical Thickness Mediates the Effect of COMT Val¹⁵⁸Met Polymorphism on Age-Associated Executive Function (Elsevier Science Inc, 2018-09-21)Proper dopamine (DA) signaling is likely necessary for maintaining optimal cognitive performance as we age, particularly in prefrontal-parietal networks and in fronto-striatal networks. Thus, reduced DA availability is a ...
(Elsevier Inc., 2019-06-13)Introduction: Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies. We aim to ...
Differential Aging Trajectories of Modulation of Activation to Cognitive Challenge in APOEε4 Groups: Reduced Modulation Predicts Poorer Cognitive Performance The present study was designed to investigate the effect of a genetic risk factor for Alzheimer's disease (AD), ApolipoproteinE ε4 (APOEε4), on the ability of the brain to modulate activation in response to cognitive ...