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Activation of the Integrated Stress Response in Nociceptors Drives Methylglyoxal-Induced Pain
(Lippincott Williams & Wilkins, 2019-01)
Methylglyoxal (MGO) is a reactive glycolytic metabolite associated with painful diabetic neuropathy at plasma concentrations between 500 nM and 5 μM. The mechanisms through which MGO causes neuropathic pain at these ...