Now showing items 1-2 of 2
Sex Differences in the Expression of Calcitonin Gene-Related Peptide Receptor Components in the Spinal Trigeminal Nucleus
(Elsevier B.V., 2019-04-24)
Background and purpose: Calcitonin gene-related peptide (CGRP) plays an important role in migraine pathophysiology. CGRP acts primarily by activating a receptor composed of 3 proteins: calcitonin receptor-like receptor ...
Protease Activated Receptor 2 (PAR2) Activation Causes Migraine-Like Pain Behaviors in Mice
(Sage Publications Ltd, 2018-05-31)
Background Pain is the most debilitating symptom of migraine. The cause of migraine pain likely requires activation of meningeal nociceptors. Mast cell degranulation, with subsequent meningeal nociceptor activation, has ...