Zheng, Jie
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Jie Zheng is an associate professor of chemistry and biochemistry and serves as the head of the Zheng Lab. His research is focused on "investigating fundamental structure-property relationships of noble metals on the nano scale and applying new functional nanoparticles in biomedical imaging and nanocatalysis." His interests include:
- Nanomaterial synthesis,
- Single-molecule microscopy and
- Bioimaging.
ORCID page
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Recent Submissions
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Activity and Pharmacology of Homemade Silver Nanoparticles in Refractory Metastatic Head and Neck Squamous Cell Cancer
(Wiley, 2018-12-11)Background Silver nanoparticles (AgNP) show efficacy in cancer cell lines. We present the first in-human outcome of AgNP in a cancer patient. Methods Homemade AgNP solution is manufactured using online instructions by a ... -
Tuning the In Vivo Transport of Anticancer Drugs Using Renal-Clearable Gold Nanoparticles
(Wiley-VCH Verlag, 2019-05-14)Precise control of in vivo transport of anticancer drugs in normal and cancerous tissues with engineered nanoparticles is key to the future success of cancer nanomedicines in clinics. This requires a fundamental understanding ... -
Photoacoustic Imaging of Nanoparticle Transport in the Kidneys at High Temporal Resolution
Noninvasive monitoring of kidney elimination of engineered nanoparticles at high temporal and spatial resolution will not only significantly advance our fundamental understandings of nephrology on the nanoscale, but also ... -
Transport and Interactions of Nanoparticles in the Kidneys
Kidneys are a major organ for blood filtration and waste elimination and thus play a key role in the transport and clearance of nanoparticles in vivo. The interactions of nanoparticles with different kidney compartments ... -
Physiological Stability and Renal Clearance of Ultrasmall Zwitterionic Gold Nanoparticles: Ligand Length Matters
(American Institute of Physics, 2017-03-15)Efficient renal clearance has been observed from ultrasmall zwitterionic glutathione-coated gold nanoparticles (GS-AuNPs), which have broad preclinical applications in cancer diagnosis and kidney functional imaging. However, ...
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