D'Mello, Santosh R.
Santosh D'Mello is a professor in the Department of Molecular and Cell Biology and holds a joint appointment with the School of Behavioral and Brain Sciences. His research has focused on neurodegeneration and neurodevelopmental disorders. Regarding the former, he is trying to understand the molecular mechanisms underlying neurodegeneration so that effective therapeutic strategies can be developed by targeting molecules that are important in controlling neuronal survival and death. In terms of neurodevelopmental disorders, Dr. D'Mello has been studying episodes of repressed gene transcription and how to control them.
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(Soc Neuroscience, 2017-07-05)Huntington's disease (HD) is an inherited neurodegenerative disease caused by a polyglutamine expansion in the huntington protein (het). The neuropathological hallmark of HD is the loss of neurons in the striatum and, to ...