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Complete Genome Analysis of Three Acinetobacter Baumannii Clinical Isolates in China for Insight into the Diversification of Drug Resistance Elements
(2013-06-24)
Background: The emergence and rapid spreading of multidrug-resistant Acinetobacter baumannii strains has become a major health threat worldwide. To better understand the genetic recombination related with the acquisition ...
Access to High School Arts Education: Why Student Participation Matters as much as Course Availability
(2013-11-04)
There is renewed interest in the role of arts education in the curriculum of U.S. public schools not only because of the intrinsic value of the arts and its believed impact on achievement, but because cultivating creativity ...
A New Catalyst-Embedded Hierarchical Air Electrode For High-Performance Li-O₂ Batteries
(2013-06-05)
The Li-O₂ battery holds great promise as an ultra-high-energy- density device. However, its limited rechargeability and low energy efficiency remain key barriers to its practical application. Herein, we demonstrate that ...
Characterizing the strand-specific distribution of non-CpG methylation in human pluripotent cells
(Oxford University Press, 2013-12-16)
DNA methylation is an important defense and regulatory mechanism. In mammals, most DNA methylation occurs at CpG sites, and asymmetric non-CpG methylation has only been detected at appreciable levels in a few cell types. ...
OLego: Fast and Sensitive Mapping of Spliced mRNA-Seq Reads Using Small Seeds
(Oxford University Press, 2013-04)
A crucial step in analyzing mRNA-Seq data is to accurately and efficiently map hundreds of millions of reads to the reference genome and exon junctions. Here we present OLego, an algorithm specifically designed for de novo ...
Transcripts for Combined Synthetic MicroRNA and Gene Delivery
(2013-06-26)
MicroRNAs (miRNAs) are a class of short noncoding RNAs which are endogenously expressed in many organisms and regulate gene expression by binding to messenger RNA (mRNA). MicroRNAs are either produced from their independent ...
Electrochemically Gated Organic Photovoltaic with Tunable Carbon Nanotube Cathodes
(2013-10-18)
We demonstrate an organic photovoltaic (OPV) device with an electrochemically gated carbon nanotube (CNT) charge collector. Bias voltages applied to the gate electrode reconfigure the common CNT electrode from an anode ...
Modeling a Sensor to Improve its Efficacy
(Hindawi Publishing Corporation, 2013-05-20)
Robots rely on sensors to provide them with information about their surroundings. However, high-quality sensors can be extremely expensive and cost-prohibitive. Thus many robotic systems must make due with lower-quality ...
Superconductivity in an inhomogeneous bundle of metallic and semiconducting nanotubes
(2013-09-06)
Using Bogoliubov-de Gennes formalism for inhomogeneous systems, we have studied superconducting properties of a bundle of packed carbon nanotubes, making a triangular lattice in the bundle's transverse cross-section. The ...
Synthetic Mammalian Transgene Negative Autoregulation
(2013-06-04)
Biological networks contain overrepresented small-scale topologies, typically called motifs. A frequently appearing motif is the transcriptional negative-feedback loop, where a gene product represses its own transcription. ...