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Exploiting the CRISPR/Cas9 PAM Constraint for Single-Nucleotide Resolution Interventions
(2016-01-20)
CRISPR/Cas9 is an enabling RNA-guided technology for genome targeting and engineering. An acute DNA binding constraint of the Cas9 protein is the Protospacer Adjacent Motif (PAM). Here we demonstrate that the PAM requirement ...
Ionosphere-Thermosphere (IT) Response to Solar Wind Forcing During Magnetic Storms
(EDP Sciences S A, 2016-01-25)
During magnetic storms, there is a strong response in the ionosphere and thermosphere which occurs at polar latitudes. Energy input in the form of Poynting flux and energetic particle precipitation, and energy output in ...
Biothermal Sensing of a Torsional Artificial Muscle
(Royal Soc Chemistry, 2016-01-25)
Biomolecule responsive materials have been studied intensively for use in biomedical applications as smart systems because of their unique property of responding to specific biomolecules under mild conditions. However, ...
Duskside Enhancement of Equatorial Zonal Electric Field Response to Convection Electric Fields During the St. Patrick's Day Storm on 17 March 2015
(Blackwell Publishing Ltd, 2016-01-11)
The equatorial zonal electric field responses to prompt penetration of eastward convection electric fields (PPEF) were compared at closely spaced longitudinal intervals at dusk to premidnight sectors during the intense ...
Highly Stretchable Hybrid Nanomembrane Supercapacitors
(2016-03-04)
Supercapacitors that are lightweight, mechanically deformable (stretchable, flexible) and electrochemically stable have potential for various applications like portable, wearable, and implantable electronics. Here we ...
Shape-Engineerable Composite Fibers and Their Supercapacitor Application
(RSC Pub, 2016-01-12)
Due to excellent electrical and mechanical properties of carbon nano materials, it is of great interest to fabricate flexible, high conductive, and shape engineered carbon based fibers. As part of these approaches, hollow, ...