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dc.contributor.authorTo, Wing Ting
dc.contributor.authorDe Ridder, Dirk
dc.contributor.authorHart, John, Jr.
dc.contributor.authorVanneste, Sven
dc.contributor.authorWang, Zijie
dc.contributor.authorPerananthan, Sahila
dc.contributor.authorPanangala, Samitha D.
dc.contributor.authorFerraris, John P.
dc.contributor.authorBalkus, Kenneth J.
dc.date.accessioned2019-05-15T21:58:27Z
dc.date.available2019-05-15T21:58:27Z
dc.date.created2018-04-13
dc.identifier.issn1533-4880
dc.identifier.urihttps://hdl.handle.net/10735.1/6494
dc.description.abstractBackground/Objective: Non-invasive neuromodulation techniques, such as repetitive Transcranial Magnetic Stimulation (rTMS) and transcranial Direct Current Stimulation (tDCS), have increasingly been investigated for their potential as treatments for neurological and psychiatric disorders. Despite widespread dissemination of these techniques, the underlying therapeutic mechanisms and the ideal stimulation site for a given disorder remain unknown. Increasing evidence support the possibility of non-invasive neuromodulation affecting a brain network rather than just the local stimulation target. In this article, we present evidence in a clinical setting to support the idea that non-invasive neuromodulation changes brain networks. Method: This article addresses the idea that non-invasive neuromodulation modulates brain networks, rather than just the local stimulation target, using neuromodulation studies in tinnitus and major depression as examples. We present studies that suppo rt this hypothesis from different perspectives. Main Results/Conclusion: Studies stimulating the same brain region, such as the dorsolateral prefrontal cortex (DLPFC), have shown to be effective for several disorders and studies using different stimulation sites for the same disorder have shown similar results. These findings, as well as results from studies investigating brain network connectivity on both macro and micro levels, suggest that non-invasive neuromodulation affects a brain network rather than just the local stimulation site targeted. We propose that non-invasive neuromodulation should be approached from a network perspective and emphasize the therapeutic potential of this approach through the modulation of targeted brain networks.
dc.relation.urihttps://doi.org/10.3389/fnhum.2018.00128
dc.rightsCC BY 4.0 (Attribution)
dc.rights©2018 The Authors
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectTranscranial Direct Current Stimulation
dc.subjectTranscranial Magnetic Stimulation
dc.subjectConnectome
dc.subjectPrefrontal Cortex
dc.titleChanging Brain Networks Through Non-Invasive Neuromodulation
dc.type.genrearticle
dc.description.departmentSchool of Behavioral and Brain Sciences
dc.identifier.bibliographicCitationTo, Wing Ting, Dirk De Ridder, John Jr Hart, Sven Vanneste, et al. 2018. "Changing brain networks through non-invasive neuromodulation." Frontiers in Human Neuroscience 12: Article 128, doi:10.3389/fnhum.2018.00128
dc.source.journalFrontiers in Human Neuroscience
dc.identifier.volume12
dc.contributor.utdAuthorTo, Wing Ting
dc.contributor.utdAuthorHart, John, Jr.
dc.contributor.utdAuthorVanneste, Sven


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