Alginate-Collagen Fibril Composite Hydrogel

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Abstract

We report on the synthesis and the mechanical characterization of an alginate-collagen fibril composite hydrogel. Native type I collagen fibrils were used to synthesize the fibrous composite hydrogel. We characterized the mechanical properties of the fabricated fibrous hydrogel using tensile testing; rheometry and atomic force microscope (AFM)-based nanoindentation experiments. The results show that addition of type I collagen fibrils improves the rheological and indentation properties of the hydrogel.

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Includes Supplementary file.
"This article belongs to the Special Issue Mechanics of Biomaterials."

Keywords

Hydrogels, Alginates, Collagen Type I, Nanoindentation, Rheometry

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CC BY 4.0 (Attribution), ©2015 The Authors

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