RNA Control in Pain: Blame it on the Messenger

Simple item page
dc.contributor.authorde la Peña, June Bryan I.
dc.contributor.authorSong, Jane J.
dc.contributor.authorCampbell, Zachary T.
dc.contributor.utdAuthorde la Peña, June Bryan I.
dc.contributor.utdAuthorSong, Jane J.
dc.contributor.utdAuthorCampbell, Zachary T.
dc.date.accessioned2020-03-10T21:17:31Z
dc.date.available2020-03-10T21:17:31Z
dc.date.issued2019-05-14
dc.descriptionDue to copyright restrictions and/or publisher's policy full text access from Treasures at UT Dallas is not available. UTD affiliates may be able to acquire a copy through Interlibrary Loan by using the link to UTD ILL.
dc.description.abstractmRNA function is meticulously controlled. We provide an overview of the integral role that posttranscriptional controls play in the perception of painful stimuli by sensory neurons. These specialized cells, termed nociceptors, precisely regulate mRNA polarity, translation, and stability. A growing body of evidence has revealed that targeted disruption of mRNAs and RNA-binding proteins robustly diminishes pain-associated behaviors. We propose that the use of multiple independent regulatory paradigms facilitates robust temporal and spatial precision of protein expression in response to a range of pain-promoting stimuli. ©2019 Wiley Periodicals, Inc.
dc.description.departmentSchool of Natural Sciences and Mathematics
dc.description.departmentCenter for Advanced Pain Studies
dc.description.sponsorshipNational Institute of Neurological Disorders and Stroke. Grant Number: R01NS100788
dc.identifier.bibliographicCitationde la Peña, J. B. I., J. J. Song, and Z. T. Campbell. 2019. "RNA control in pain: Blame it on the messenger." Wiley Interdisciplinary Reviews: RNA 10(6): e1546, doi: 10.1002/wrna.1546
dc.identifier.issn1757-7004
dc.identifier.issue6
dc.identifier.urihttp://dx.doi.org/10.1002/wrna.1546
dc.identifier.urihttps://hdl.handle.net/10735.1/7385
dc.identifier.volume10
dc.language.isoen
dc.publisherBlackwell Publishing Ltd
dc.rights©2019 Wiley Periodicals, Inc.
dc.source.journalWiley Interdisciplinary Reviews: RNA
dc.subjectNociceptors
dc.subjectPain
dc.subjectPlasticity
dc.subjectRNA
dc.titleRNA Control in Pain: Blame it on the Messenger
dc.type.genrearticle

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
NSM-7128-261009.40-UTD ILL.pdf
Size:
164.88 KB
Format:
Adobe Portable Document Format
Description:
Link to UTD ILL
Download

Collections

CAPS Research