Optical Architecture Design for Detection of Absorbers Embedded in Visceral Fat

Optically absorbing ducts embedded in scattering adipose tissue can be injured during laparoscopic surgery. Non-sequential simulations and theoretical analysis compare optical system configurations for detecting these absorbers. For absorbers in deep scattering volumes, trans-illumination is preferred instead of diffuse reflectance. For improved contrast, a scanning source with a large area detector is preferred instead of a large area source with a pixelated detector.