Enhancement of the Electrical Properties of DNA Molecular Wires Through Incorporation of Perylenediimide DNA Base Surrogates



DNA has long been viewed as a promising material for nanoscale electronics, in part due to its well-ordered arrangement of stacked, pi-conjugated base pairs. Within this context, a number of studies have investigated how structural changes, backbone modifications, or artificial base substitutions affect the conductivity of DNA. Herein, we present a comparative study of the electrical properties of both well-matched and perylene-3,4,9,10-tetracarboxylic diimide (PTCDI)-containing DNA molecular wires that bridge nanoscale gold electrodes. By performing current-voltage measurements for such devices, we find that the incorporation of PTCDI DNA base surrogates within our macromolecular constructs leads to an approximately 6-fold enhancement in the observed current levels. Together, these findings suggest that PTCDI DNA base surrogates may enable the preparation of designer DNA-based nanoscale electronic components. © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim


CMMI-1246762; Air Force Office of Scientific Research. Grant Number: FA9550-13-1-0096; Office of Naval Research. Grant Number: N00014-16-1-2741.
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Bioelectronics, Nanoelectromechanical systems, Nanotechnology, perylene-3,4,9,10-tetracarboxylic diimide



©2019 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim