Polarity Specific Suppression Effects of Transcranial Direct Current Stimulation for Tinnitus

dc.contributor.authorJoos, Kathleenen_US
dc.contributor.authorDe Ridder, Dirken_US
dc.contributor.authorVan, de Heyningen_US
dc.contributor.authorVanneste, Svenen_US
dc.date.accessioned2014-09-12T16:41:23Z
dc.date.available2014-09-12T16:41:23Z
dc.date.created2014-04-10
dc.description.abstractTinnitus is the perception of a sound in the absence of an external auditory stimulus and affects 10-15% of the Western population. Previous studies have demonstrated the therapeutic effect of anodal transcranial direct current stimulation (tDCS) over the left auditory cortex on tinnitus loudness, but the effect of this presumed excitatory stimulation contradicts with the underlying pathophysiological model of tinnitus. Therefore, we included 175 patients with chronic tinnitus to study polarity specific effects of a single tDCS session over the auditory cortex (39 anodal, 136 cathodal). To assess the effect of treatment, we used the numeric rating scale for tinnitus loudness and annoyance. Statistical analysis demonstrated a significant main effect for tinnitus loudness and annoyance, but for tinnitus annoyance anodal stimulation has a significantly more pronounced effect than cathodal stimulation. We hypothesize that the suppressive effect of tDCS on tinnitus loudness may be attributed to a disrupting effect of ongoing neural hyperactivity, independent of the inhibitory or excitatory effects and that the reduction of annoyance may be induced by influencing adjacent or functionally connected brain areas involved in the tinnitus related distress network. Further research is required to explain why only anodal stimulation has a suppressive effect on tinnitus annoyance. ;en_US
dc.identifier.bibliographicCitationJoos, Kathleen, Dirk De Ridder, de Heyning Van, and Sven Vanneste. 2014. "Polarity specific suppression effects of transcranial direct current stimulation for tinnitus." Neural Plasticity 2014(930860): 1-9.en_US
dc.identifier.issn1687-5443en_US
dc.identifier.issue930860en_US
dc.identifier.urihttp://hdl.handle.net/10735.1/4010
dc.identifier.volume2014en_US
dc.publisherHindawi Pub. Corpen_US
dc.relation.urihttp://dx.doi.org/10.1155/2014/930860en_US
dc.rightsCC BY 3.0 (Attribution)en_US
dc.rights©2014 The Authorsen_US
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/en_US
dc.source.journalNeural Plasticityen_US
dc.subjectTinnitusen_US
dc.subjectElectric stimulationen_US
dc.subjectAuditory cortexen_US
dc.subjectTranscranial direct current stimulation (tDCS)en_US
dc.titlePolarity Specific Suppression Effects of Transcranial Direct Current Stimulation for Tinnitusen_US
dc.typeTexten_US
dc.type.genrearticleen_US

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