Cyclopamine Tartrate, An Inhibitor of Hedgehog Signaling, Strongly Interferes with Mitochondrial Function and Suppresses Aerobic Respiration in Lung Cancer Cells

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dc.contributor.ORCID0000-0003-0867-2189 (Lou, X)en_US
dc.contributor.VIAF250674117 (Izen, JM)en_US
dc.contributor.authordel Amo Sanchez. P.en_US
dc.contributor.authorLees, J. P.en_US
dc.contributor.authorPoireau, V.en_US
dc.contributor.authorTisserand, V.en_US
dc.contributor.authorGrauges, E.en_US
dc.contributor.authorPalano, A.en_US
dc.contributor.authorEigen, G.en_US
dc.contributor.authorIzen, Joseph M.en_US
dc.contributor.authorLou, Xinchouen_US
dc.contributor.utdAuthorIzen, Joseph M.en_US
dc.contributor.utdAuthorLou, Xinchouen_US
dc.date.accessioned2017-11-30T23:31:03Z
dc.date.available2017-11-30T23:31:03Z
dc.date.created2016-03-29en_US
dc.date.issued2016-03-29en_US
dc.description.abstractWe measure the time-dependent CP asymmetry in the radiative-penguin decay B0→KS0π-π+γ, using a sample of 471×106 (4S)→BB-events recorded with the BABAR detector at the PEP-II e+e- storage ring at SLAC. Using events with mKππ<1.8 GeV/c2, we measure the branching fractions of B+→K+π-π+γ and B0→K0π-π+γ, the branching fractions of the kaonic resonances decaying to K+π-π+, as well as the overall branching fractions of the B+→ρ0K+γ, B+→K∗0π+γ and S-wave B+→(Kπ)0∗0π+γ components. For events from the ρ mass band, we measure the CP-violating parameters SKS0π+π-γ=0.14±0.25±0.03 and CKS0π+π-γ=-0.39±0.20-0.02+0.03, where the first uncertainties are statistical and the second are systematic. We extract from this measurement the time-dependent CP asymmetry related to the CP eigenstate ρ0KS0 and obtain SKS0ργ=-0.18±0.32-0.05+0.06, which provides information on the photon polarization in the underlying b→sγ transition.en_US
dc.identifier.bibliographicCitationdel Amo Sanchez, P., J. P. Lees, V. Poireau, V. Tisserand, et al. 2016. "Time-dependent analysis of B⁰ → K_s⁰ π⁻π⁺γ decays and studies of the K⁺π⁻π⁺ system in B⁺ → K⁺π⁻π⁺γ decays." Physical Review D - Particles, Fields, Gravitation and Cosmology 93(5), doi:10.1103/PhysRevD.93.052013en_US
dc.identifier.issn1550-7998en_US
dc.identifier.issue5en_US
dc.identifier.urihttp://hdl.handle.net/10735.1/5602
dc.identifier.volume93en_US
dc.language.isoenen_US
dc.publisherAmerican Physical Societyen_US
dc.relation.urihttp://dx.doi.org/10.1103/PhysRevD.93.052013
dc.rights©2016 American Physical Society. All Rights Reserved.en_US
dc.sourcePhysical Review D - Particles, Fields, Gravitation and Cosmology
dc.subjectBranching fractions (Nuclear physics)en_US
dc.subjectCausality (Physics)en_US
dc.subjectKaonsen_US
dc.subjectLeptonic decaysen_US
dc.subjectMagnetic fieldsen_US
dc.subjectResonanceen_US
dc.subjectMesonsen_US
dc.titleCyclopamine Tartrate, An Inhibitor of Hedgehog Signaling, Strongly Interferes with Mitochondrial Function and Suppresses Aerobic Respiration in Lung Cancer Cellsen_US
dc.type.genrearticleen_US

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Izen, Joseph M.
Lou, Xinchou