Song, BoWu, YunkouYu, MengxiaoZhao, PiyuZhou, ChenKiefer, Garry E.Sherry, A. Dean2014-08-222014-08-222013-04-042013-04-041477-9234http://hdl.handle.net/10735.1/3918Includes supplementary material.A europium(Ⅲ) DOTA-tetraamide complex was designed as a MRI sensor of singlet oxygen (¹O₂). The water soluble, thermodynamically stable complex reacts rapidly with ¹O₂ to form an endoperoxide derivative that results in an ~3 ppm shift in the position of the Eu(Ⅲ)-bound water chemical exchange saturation transfer (CEST) peak. The potential of using this probe to detect accumulation of the endoperoxide derivative in biological media by ratiometric CEST imaging was demonstrated.;©2013 The Royal Society of Chemistry. This article may not be further made available or distributed.Active oxygenMagnetic resonance imagingChemical Exchange Saturation Transfer (CEST)ArticleSong, Bo, Yunkou Wu, Mengxiao Yu, Piyu Zhao, et al. 2013. "A europium(Ⅲ)-based PARACEST agent for sensing singlet oxygen by MRI." Dalton Transactions 42(22): 8066-806942228066