Lin, Kuo-YaoBurke, A.King, Nolan B.Kahanda, DimithreeMazaheripour, A.Bartlett, A.Dibble, D. J.McWilliams, Mark A.Taylor, David W.Jocson, J. -MMinary-Jolandan, MajidGorodetsky, A. A.Slinker, Jason D.2020-02-192020-02-192019-04-252192-6506http://dx.doi.org/10.1002/cplu.201800661https://hdl.handle.net/10735.1/7282CMMI-1246762; Air Force Office of Scientific Research. Grant Number: FA9550-13-1-0096; Office of Naval Research. Grant Number: N00014-16-1-2741.Due to copyright restrictions and/or publisher's policy full text access from Treasures at UT Dallas is not available. UTD affiliates may be able to acquire a copy by using the link below to contact university Interlibrary Loan.DNA has long been viewed as a promising material for nanoscale electronics, in part due to its well-ordered arrangement of stacked, pi-conjugated base pairs. Within this context, a number of studies have investigated how structural changes, backbone modifications, or artificial base substitutions affect the conductivity of DNA. Herein, we present a comparative study of the electrical properties of both well-matched and perylene-3,4,9,10-tetracarboxylic diimide (PTCDI)-containing DNA molecular wires that bridge nanoscale gold electrodes. By performing current-voltage measurements for such devices, we find that the incorporation of PTCDI DNA base surrogates within our macromolecular constructs leads to an approximately 6-fold enhancement in the observed current levels. Together, these findings suggest that PTCDI DNA base surrogates may enable the preparation of designer DNA-based nanoscale electronic components. © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheimen©2019 Wiley‐VCH Verlag GmbH & Co. KGaA, WeinheimBioelectronicsNanoelectromechanical systemsNanotechnologyperylene-3,4,9,10-tetracarboxylic diimidearticleLin, K. -Y, A. Burke, N. B. King, D. Kahanda, et al. 2019. "Enhancement of the Electrical Properties of DNA Molecular Wires through Incorporation of Perylenediimide DNA Base Surrogates." Chempluschem 84(4): 416-419, doi: 10.1002/cplu.201800661844