Nagai, A.Miller, J. B.Du, JiaKos, P.Stefan, Mihaela C.Siegwart, D. J.2015-09-112015-09-112015-06-192015-06-191359-7345http://hdl.handle.net/10735.1/4602Includes correction published 2015-11-10Using a bio-inspired cellulose template, new charge transfer (CT) nanoparticles (NPs) with unique and intriguing emission properties are reported. Pyrene-modified 2,3-di-O-methyl cellulose formed CT complexes with small molecule acceptors, e.g. 7,7,8,8-tetracyanoquinodimethane (TCNQ), and exhibited aggregation-induced emission (AIE) in aqueous medium upon nanoparticle formation. The TCNQ-CT NPs showed multicolor fluorescence emissions at 370-400 nm, 602 nm and 777 nm, when excited at 330 nm, 485 nm and 620 nm respectively. The cellulose-TCNQ NPs are biocompatible and demonstrate an advance in the use of the CT mechanism for biomedical imaging applications both in vitro and in vivo.en©2015 The Royal Society of Chemistry. This article may not be further made available or distributed.TetracyanoquinodimethaneCelluloseMethaneNanoparticlesPyrene (Chemical)Unclassified drugAbsorptionAnimals--ExperimentsBiocompatibilityConfocal microscopyEsterificationFluorescenceGel permeation chromatographyInfrared spectroscopyMelanomaMolecular weightsNuclear magnetic resonancePhotoluminescenceThermogravimetryArticleNagai, A., J. B. Miller, J. Du, P. Kos, et al. 2015. "Biocompatible organic charge transfer complex nanoparticles based on a semi-crystalline cellulose template." Chemical Communications 51(59): 11868-11871 doi:10.1039/C5CC03822G5159