Liao, WillOuyang, WeimingZhang, Michael Q.Li, Ming O.2015-01-232015-01-232014-08-012014-08-012213-5960http://hdl.handle.net/10735.1/4284The Forkhead box O (Foxo) family of transcription factors has a critical role in controlling the development, differentiation, and function of T cells. However, the direct target genes of Foxo transcription factors in T cells have not been well characterized. In this study, we focused on mapping the genome wide Foxo1-binding sites in naïve CD4(+) T cells, CD8(+) T cells, and Foxp3(+) regulatory T (Treg) cells. By using chromatin immunoprecipitation coupled with deep sequencing (ChIP-Seq), we identified Foxo1 binding sites that were shared among or specific to the three T cell populations. Here we describe the experiments, quality controls, as well as the deep sequencing data. Part of the data analysis has been published by Ouyang W et al. in Nature 20121] and Kim MV et al. in Immunity 20132], and the associated data set were uploaded to NCBI Gene Expression Omnibus.;CC BY-NC-ND 3.0 (Attribution-NonCommercial-NoDerivatives)©2014 The Authorshttp://creativecommons.org/licenses/by-nc-nd/3.0/T-LymphocytesFoxo1 protein, mouseGenomesFoxp3 protein, mousebirA proteinArticleLiao, Will, Weiming Ouyang, Michael Q. Zhang, and Ming O. Li. 2014. "Genome wide mapping of Foxo1 binding-sites in murine T lymphocytes." Genomics Data 2: 280-281.2