Biocompatible Organic Charge Transfer Complex Nanoparticles Based on a Semi-Crystalline Cellulose Template

dc.contributor.VIAF55039821 (Stefan, MC)
dc.contributor.authorNagai, A.en_US
dc.contributor.authorMiller, J. B.en_US
dc.contributor.authorDu, Jiaen_US
dc.contributor.authorKos, P.en_US
dc.contributor.authorStefan, Mihaela C.en_US
dc.contributor.authorSiegwart, D. J.en_US
dc.contributor.utdAuthorStefan, Mihaela C.en_US
dc.date.accessioned2015-09-11T22:24:53Z
dc.date.available2015-09-11T22:24:53Z
dc.date.created2015-06-19en_US
dc.date.issued2015-06-19en_US
dc.descriptionIncludes correction published 2015-11-10en_US
dc.description.abstractUsing a bio-inspired cellulose template, new charge transfer (CT) nanoparticles (NPs) with unique and intriguing emission properties are reported. Pyrene-modified 2,3-di-O-methyl cellulose formed CT complexes with small molecule acceptors, e.g. 7,7,8,8-tetracyanoquinodimethane (TCNQ), and exhibited aggregation-induced emission (AIE) in aqueous medium upon nanoparticle formation. The TCNQ-CT NPs showed multicolor fluorescence emissions at 370-400 nm, 602 nm and 777 nm, when excited at 330 nm, 485 nm and 620 nm respectively. The cellulose-TCNQ NPs are biocompatible and demonstrate an advance in the use of the CT mechanism for biomedical imaging applications both in vitro and in vivo.en_US
dc.description.sponsorship"D.J.S. acknowledges grant support from the Cancer Prevention and Research Institute of Texas (CPRIT) (R1212) and the Welch Foundation (I-1855). J.B.M. acknowledges fellowship support from CPRIT (RP140110). M.C.S. acknowledges grant support from the Welch Foundation (AT-1740), the NSF (Career DMR-0956116), and the NSF-MRI (CHE-1126177)."en_US
dc.identifier.bibliographicCitationNagai, A., J. B. Miller, J. Du, P. Kos, et al. 2015. "Biocompatible organic charge transfer complex nanoparticles based on a semi-crystalline cellulose template." Chemical Communications 51(59): 11868-11871 doi:10.1039/C5CC03822Gen_US
dc.identifier.issn1359-7345en_US
dc.identifier.issue59en_US
dc.identifier.urihttp://hdl.handle.net/10735.1/4602
dc.identifier.volume51en_US
dc.language.isoenen_US
dc.publisherRoyal Society of Chemistryen_US
dc.relation.urihttp://dx.doi.org/10.1039/c5cc03822g
dc.rights©2015 The Royal Society of Chemistry. This article may not be further made available or distributed.en_US
dc.sourceChemical Communications
dc.subjectTetracyanoquinodimethaneen_US
dc.subjectCelluloseen_US
dc.subjectMethaneen_US
dc.subjectNanoparticlesen_US
dc.subjectPyrene (Chemical)en_US
dc.subjectUnclassified drugen_US
dc.subjectAbsorptionen_US
dc.subjectAnimals--Experimentsen_US
dc.subjectBiocompatibilityen_US
dc.subjectConfocal microscopyen_US
dc.subjectEsterificationen_US
dc.subjectFluorescenceen_US
dc.subjectGel permeation chromatographyen_US
dc.subjectInfrared spectroscopyen_US
dc.subjectMelanomaen_US
dc.subjectMolecular weightsen_US
dc.subjectNuclear magnetic resonanceen_US
dc.subjectPhotoluminescenceen_US
dc.subjectThermogravimetryen_US
dc.titleBiocompatible Organic Charge Transfer Complex Nanoparticles Based on a Semi-Crystalline Cellulose Templateen_US
dc.type.genreArticleen_US

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