Validation and Interpretable Model Explanations for Synthesized Data in Healthcare

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dc.contributor.advisorPrabhakaran, Balakrishnan
dc.creatorMaweu, Barbara Mukami
dc.creator.orcid0000-0002-5877-8822
dc.date.accessioned2022-08-23T20:08:34Z
dc.date.available2022-08-23T20:08:34Z
dc.date.created2021-08
dc.date.issued2021-07-16
dc.date.submittedAugust 2021
dc.date.updated2022-08-23T20:08:35Z
dc.description.abstractRecent advances in artificial intelligence (AI) based solutions for healthcare problems have led to the increased demands for quality accessible patient data and the functional understanding of the remarkable outcomes of AI decision support systems. Nonetheless, challenges persist from strict regulations that oversee patient privacy, small imbalanced datasets due to high costs of measurement and expert annotation, and the black-box nature of AI technology. In this dissertation, we address foundational frameworks necessary for achieving quality and accessible synthesized healthcare time-series data and build the essential trust and confidence in outcomes of AI solutions through interpretable explanations for healthcare time series data. In the first challenge, we propose validation approaches for synthesized healthcare time-series data and apply this quality synthesized data in training better performing healthcare decision support systems. Finally, we present a framework that generates and integrates modular interpretable explanations from varying deep learning models with model capacities achieved using synthesized data.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/10735.1/9459
dc.language.isoen
dc.subjectMedical care
dc.subjectArtificial intelligence
dc.titleValidation and Interpretable Model Explanations for Synthesized Data in Healthcare
dc.typeThesis
dc.type.materialtext
thesis.degree.departmentSoftware Engineering
thesis.degree.grantorThe University of Texas at Dallas
thesis.degree.levelDoctoral
thesis.degree.namePHD

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