Genome Wide Mapping of Foxo1 Binding-Sites in Murine T Lymphocytes
| dc.contributor.author | Liao, Will | en_US |
| dc.contributor.author | Ouyang, Weiming | en_US |
| dc.contributor.author | Zhang, Michael Q. | en_US |
| dc.contributor.author | Li, Ming O. | en_US |
| dc.contributor.utdAuthor | Zhang, Michael Q. | en_US |
| dc.date.accessioned | 2015-01-23T22:07:43Z | |
| dc.date.available | 2015-01-23T22:07:43Z | |
| dc.date.created | 2014-08-01 | en_US |
| dc.date.issued | 2014-08-01 | en_US |
| dc.description.abstract | The Forkhead box O (Foxo) family of transcription factors has a critical role in controlling the development, differentiation, and function of T cells. However, the direct target genes of Foxo transcription factors in T cells have not been well characterized. In this study, we focused on mapping the genome wide Foxo1-binding sites in naïve CD4(+) T cells, CD8(+) T cells, and Foxp3(+) regulatory T (Treg) cells. By using chromatin immunoprecipitation coupled with deep sequencing (ChIP-Seq), we identified Foxo1 binding sites that were shared among or specific to the three T cell populations. Here we describe the experiments, quality controls, as well as the deep sequencing data. Part of the data analysis has been published by Ouyang W et al. in Nature 20121] and Kim MV et al. in Immunity 20132], and the associated data set were uploaded to NCBI Gene Expression Omnibus.; | en_US |
| dc.description.sponsorship | US National Institutes of Health (R01 AI102888/AI/NIAID) | en_US |
| dc.identifier.bibliographicCitation | Liao, Will, Weiming Ouyang, Michael Q. Zhang, and Ming O. Li. 2014. "Genome wide mapping of Foxo1 binding-sites in murine T lymphocytes." Genomics Data 2: 280-281. | en_US |
| dc.identifier.issn | 2213-5960 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10735.1/4284 | |
| dc.identifier.volume | 2 | en_US |
| dc.publisher | Elsevier Inc | en_US |
| dc.relation.uri | http://dx.doi.org/10.1016/j.gdata.2014.0/8.006 | |
| dc.rights | CC BY-NC-ND 3.0 (Attribution-NonCommercial-NoDerivatives) | en_US |
| dc.rights | ©2014 The Authors | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/ | en_US |
| dc.source | Genomics Data | |
| dc.subject | T-Lymphocytes | en_US |
| dc.subject | Foxo1 protein, mouse | en_US |
| dc.subject | Genomes | en_US |
| dc.subject | Foxp3 protein, mouse | en_US |
| dc.subject | birA protein | en_US |
| dc.title | Genome Wide Mapping of Foxo1 Binding-Sites in Murine T Lymphocytes | en_US |
| dc.type.genre | Article | en_US |
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